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Little Red Door Cancer Agency was originally established in 1945 as the Indiana Cancer Society. Functioning as an educational outlet at its inception, Little Red Door provided information on the symptoms of cancer. It was located at 1101 West 10th Street in a World War II barrack that had been refurbished, complete with a red door. Since the word cancer carried a social stigma at the time, Little Red Door became more commonly used than the agency’s official name.

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